Ethyl 1-(4-nitrophenyl)-4-piperidinecarboxylate
Ethyl 1-(4-nitrophenyl)-4-piperidinecarboxylate
CAS: 216985-30-7
Molecular Formula: C14H18N2O4
Ethyl 1-(4-nitrophenyl)-4-piperidinecarboxylate - Names and Identifiers
Ethyl 1-(4-nitrophenyl)-4-piperidinecarboxylate - Physico-chemical Properties
| Molecular Formula | C14H18N2O4 |
| Molar Mass | 278.3 |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD00205918 |
Ethyl 1-(4-nitrophenyl)-4-piperidinecarboxylate - Risk and Safety
| Hazard Class | IRRITANT |
Ethyl 1-(4-nitrophenyl)-4-piperidinecarboxylate - Introduction
Ethyl acetate 1-(4-nitrophenyl)-4-piperidinecarboxylate (Ethyl 1-(4-nitrophenyl)-4-piperidinecarboxylate) is an organic compound. The following is a description of its properties, uses, preparation methods and safety information:
Nature:
-Appearance: It is usually yellow to orange crystalline or powdered.
-Molecular formula: C16H20N2O4
-Molecular weight: 312.34g/mol
-Melting point: about 84-88°C
-Boiling point: about 435-437°C
-Solubility: It dissolves in common organic solvents.
Use:
-Ethyl acetate Ethyl 1-(4-nitrophenyl)-4-piperidinecarboxylate is a chemical intermediate commonly used in organic synthesis reactions.
-It can be used to synthesize drugs, dyes and other organic compounds.
Preparation Method:
-Ethyl acetate 1-(4-nitrophenyl)-4-piperidinecarboxylic acid ethyl ester preparation method includes the following steps:
1. nitrobenzene and cyanide iron (III) reaction to generate nitroaniline.
2. reaction of nitroaniline and piperidine to generate ethyl acetate 1-(4-nitrophenyl)-4-piperidinamine.
3. ethyl acetate 1-(4-nitrophenyl)-4-piperidinamine is reacted with anhydrous hydrochloric acid to generate ethyl acetate 1-(4-nitrophenyl)-4-piperidine carboxylate.
4. Finally, ethyl acetate 1-(4-nitrophenyl)-4-piperidinecarboxylate is reacted with an inorganic base to obtain ethyl acetate 1-(4-nitrophenyl)-4-piperidinecarboxylate.
Safety Information:
-Ethyl acetate Ethyl 1-(4-nitrophenyl)-4-piperidinecarboxylate may be a chemical harmful to the eyes, skin and respiratory system.
-Follow safe operating procedures during use or handling, including wearing appropriate protective equipment (such as gloves, goggles, and protective masks).
-Keep away from fire and heat sources to avoid the risk of fire and explosion.
-If inhaled or exposed to the compound, wash the affected area immediately and seek medical help.
Nature:
-Appearance: It is usually yellow to orange crystalline or powdered.
-Molecular formula: C16H20N2O4
-Molecular weight: 312.34g/mol
-Melting point: about 84-88°C
-Boiling point: about 435-437°C
-Solubility: It dissolves in common organic solvents.
Use:
-Ethyl acetate Ethyl 1-(4-nitrophenyl)-4-piperidinecarboxylate is a chemical intermediate commonly used in organic synthesis reactions.
-It can be used to synthesize drugs, dyes and other organic compounds.
Preparation Method:
-Ethyl acetate 1-(4-nitrophenyl)-4-piperidinecarboxylic acid ethyl ester preparation method includes the following steps:
1. nitrobenzene and cyanide iron (III) reaction to generate nitroaniline.
2. reaction of nitroaniline and piperidine to generate ethyl acetate 1-(4-nitrophenyl)-4-piperidinamine.
3. ethyl acetate 1-(4-nitrophenyl)-4-piperidinamine is reacted with anhydrous hydrochloric acid to generate ethyl acetate 1-(4-nitrophenyl)-4-piperidine carboxylate.
4. Finally, ethyl acetate 1-(4-nitrophenyl)-4-piperidinecarboxylate is reacted with an inorganic base to obtain ethyl acetate 1-(4-nitrophenyl)-4-piperidinecarboxylate.
Safety Information:
-Ethyl acetate Ethyl 1-(4-nitrophenyl)-4-piperidinecarboxylate may be a chemical harmful to the eyes, skin and respiratory system.
-Follow safe operating procedures during use or handling, including wearing appropriate protective equipment (such as gloves, goggles, and protective masks).
-Keep away from fire and heat sources to avoid the risk of fire and explosion.
-If inhaled or exposed to the compound, wash the affected area immediately and seek medical help.
Last Update：2024-04-09 21:00:56
